There is not much to be said here. When you select Audio from the Settings menu in the main window, you are presented with this dialog.
Nominal configurability is granted with ALSA. However, I don't recommend using it. JACK is The Way. It's also easy to configure Specimen for it, as you can see. Take note of the Stop button for ALSA and the Disconnect button for JACK. This will allow you to change which audio interface you are using without restarting Specimen. This is convenient if you have already set up an intricate arrangement of synths and sequencers. If you close Specimen, you will break it's connection with whatever sequencer you were using, and you will not be able to restore it unless you start Specimen before you start your sequencer. This is a pain which the aforementioned buttons should help you avoid.
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